Exosomes vs. PRP Plus: The 2026 Guide to Non-Surgical Hair Restoration
Compare Exosomes vs PRP Plus for hair restoration. Discover which biological foundation is right for your hair loss treatment.
Exosomes vs. PRP Plus: The 2026 Guide to Non-Surgical Hair Restoration
Published: 2026-01-15
Reading time: 8 min
In the rapidly evolving world of aesthetic medicine, 2026 has marked a shift from maintenance to regeneration. If you are deciding between PRP Plus and Exosomes, this guide breaks down the science, comfort, cost, and outcomes.
At a Glance: The Comparison
| Feature | PRP Plus (Platelet-Rich Plasma) | Exosomes (e.g., Purasomes) |
|---|---|---|
| Core Technology | Autologous (your own blood) | Lab-purified extracellular vesicles |
| Primary Action | "The Fertilizer" Feeds follicles with nutrients & growth factors | "The Manager" Signals stem cells to wake up & repair |
| Concentration | ~5-7x baseline growth factors | ~1000x growth factors vs PRP |
| Invasiveness | 🟡 Medium (blood draw + injections) | 🟢 Low (no blood draw + microneedling) |
| Pain Level | 🟡 Moderate (5/10) - pressure/sting | 🟢 Low (2/10) - mild vibration/scratch |
| Inflammation | Pro-inflammatory (triggers healing) | Anti-inflammatory (calms scalp) |
| Best Candidates | Early thinning, prefers natural/autologous | Advanced thinning, older patients, autoimmune |
| Avg. Cost (Vancouver) | ~$800 CAD / session | ~$850-$1,200 CAD / session |
What is PRP Plus? (The “Fertilizer”)
PRP Plus uses your own blood. We draw a small sample, concentrate platelets, and re-inject the plasma rich in growth factors into the scalp. The goal is to kick-start repair by creating a controlled healing response.
Why patients choose PRP Plus:
- 100% autologous (your own biological material)
- Widely studied with long clinical history
- Good option for early hair thinning
Limitations to know:
- Requires blood draw and injections
- Inflammation can cause temporary scalp sensitivity
- Results depend on individual platelet quality
What are Exosomes? (The “Manager”)
Exosomes are lab-purified signaling packets derived from stem cell cultures. Instead of feeding follicles, they deliver instructions that tell stem cells to activate, repair, and shift the scalp into a pro-growth environment.
Why patients choose Exosomes:
- Higher concentration of regenerative signals
- Lower discomfort during treatment
- Powerful anti-inflammatory effect for sensitive scalps
Limitations to know:
- Premium cost compared to PRP
- Requires reputable clinical sourcing and handling
Which One Works Better?
PRP Plus is excellent for early thinning, younger patients, and those who prefer a natural approach.
Exosomes often perform better for advanced hair loss, inflammation-related shedding, and patients who want faster visible improvement.
In practice, many clients see the best results by starting with Exosomes and maintaining with PRP Plus.
Safety & Downtime
Both are non-surgical with minimal downtime. Most clients return to normal activities within 24 hours.
- PRP Plus: possible mild swelling, tenderness, temporary redness
- Exosomes: mild redness from microneedling, minimal soreness
Cost & Value
PRP Plus is more affordable per session, while Exosomes typically deliver stronger results per treatment. We evaluate long-term value based on your hair density goals, scalp condition, and budget.
RAAC Clinical Approach
At RAAC, we personalize every hair restoration plan based on:
- Scalp analysis and hair density mapping
- Medical history and inflammatory markers
- Hair growth goals and timeline
We also combine regenerative therapies with supportive protocols (nutrition, supplementation, and maintenance scheduling) to maximize results.
FAQs
Q: Which is better for autoimmune-related hair loss?
A: Exosomes generally perform better due to stronger anti-inflammatory signaling.
Q: How soon will I see results?
A: Most clients notice reduced shedding in 4-6 weeks. Visible density improvements often appear in 3-6 months.
Q: Can I combine Exosomes with PRP?
A: Yes. Combination protocols are often used to accelerate and maintain results.
Book a Consultation
We can help you choose the right protocol based on your scalp condition and goals. Book a consultation to review your options and build a safe treatment plan.
Medical disclaimer: This article is for educational purposes and does not replace medical advice. Treatments should be prescribed and monitored by licensed clinicians.
